Educational Resources

Time-Resolved Macromolecular Crystallography and Solution Scattering

• Malla, T. N., and Schmidt, M. Transient state measurements on proteins by time-resolved crystallography. Current Opinion in Structural Biology 74, 102376 (2022) Abstract
• Westenhoff, S., Meszaros, P., and Schmidt, M. Protein motions visualized by femtosecond time-resolved crystallography: The case of photosensory vs photosynthetic proteins. Current Opinion in Structural Biology 77, 102481 (2022) Abstract
• Schulz, E. C., Yorke, B. A., Pearson, A. R., and Mehrabi, P. Best practices for time-resolved serial synchrotron crystallography. Acta Cryst D 78, 14–29 (2022) Abstract
• Brändén, G., and Neutze, R. Advances and challenges in time-resolved macromolecular crystallography. Science 373, eaba0954 (2021) Abstract
• Monteiro, D. C. F., Amoah, E., Rogers, C., and Pearson, A. R. Using photocaging for fast time-resolved structural biology studies. Acta Crystallogr D Struct Biol 77, 1218–1232 (2021) Abstract
• Pearson, A. R., and Mehrabi, P. Serial synchrotron crystallography for time-resolved structural biology. Current Opinion in Structural Biology 65, 168–174 (2020) Abstract
• Schmidt, M. Time-Resolved Macromolecular Crystallography at Pulsed X-ray Sources. International Journal of Molecular Sciences 20, 1401 (2019) Abstract
• Moffat, K.  CHAPTER 5:Dynamic and Static X-ray Scattering from Biological Systems on the Femtosecond to Nanosecond Time Scale.  X-Ray FREE ELECTRON LASERS, pp 105-127 (2017) Abstract
• Srajer, V., and Schmidt, M.  Watching proteins function with time-resolved x-ray crystallography.  J. Phys. D: Appl. Phys. (2017) Abstract
• Schmidt, M.  Time-Resolved Macromolecular Crystallography at Modern X-Ray Sources.  Protein Crystallography, pp 273–294. Humana Press, New York, NY. (2017) Abstract
• Sui, S., and Perry, S. L.  Microfluidics: From crystallization to serial time-resolved crystallography.  Structural Dynamics 4, 032202 (2017) Abstract
• Kim, J., Kim, K. H., Oang, K. Y., Lee, J. H., Hong, K., Cho, H., Huse, N., Schoenlein, R. W., Kim, T. K., and Ihee, H.  Tracking reaction dynamics in solution by pump–probe X-ray absorption spectroscopy and X-ray liquidography (solution scattering).  Chem. Commun. 52, 3734–3749 (2016) Abstract
• Schotte, F., Cho, H. S., Kamikubo, H., Kataoka, M., and Anfinrud, P. A.  Watching a Signaling Protein Function in Real Time via Picosecond Time-Resolved Laue Crystallography.  Molecular Science of Fluctuations Toward Biological Functions (Terazima, M., Kataoka, M., Ueoka, R., and Okamoto, Y., Eds.),
  pp 65–85. Springer Japan (2015)
• J. G. Kim, T. W. Kim, J. Kim and H. Ihee.  Protein Structural Dynamics Revealed by Time-Resolved X-ray Solution Scattering.  Accounts of Chemical Research 48, 2200–2208 (2015) Abstract
• M. Schmidt.  Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources.  Synchrotron Radiation News 28, 25–30 (2015) Abstract
• Keith Moffat.  Time-resolved crystallography and protein design: signaling photoreceptors and optogenetics.  Phil. Trans. R. Soc. B 369, 20130568 (2014) Abstract
• V. Šrajer: Time-resolved Macromolecular Crystallography in Practice at BioCARS, Advanced Photon Source: From Data Collection to Structures of Intermediates.  The Future of Dynamic Structural Science, NATO Science for Peace and Security Series A: Chemistry and Biology (J.A.K. Howard, et al, Eds.), Springer Science+Business Media Dordrecht, Chapter 17, pp. 237-251 (2014) (Abstract)
• Zhong Ren.  Laue Data Processing with Precognition
• M. Schmidt, V. Srajer, R. Henning, H. Ihee, N. Purwar, J. Tenboer and S. Tripathi.  Protein energy landscapes determined by five-dimensional crystallography.  Acta Cryst. D Biological Crystallography 69, 2534–2542 (2013)
• R. Neutze and K. Moffat.  Time-resolved structural studies at synchrotrons and X-ray free electron lasers: opportunities and challenges.  Curr. Opin. Struct. Biol. 22, 651–659 (2012)
• D. Bourgeois, M. Weik.  Kinetic protein crystallography: a tool to watch proteins in action.  Crystallography Reviews 15 (2) 87-118 (2009) Abstract
• M. Schmidt.  Structure-based kinetics by time-resolved X-ray crystallography.  In Ultrashort Laser Pulses in Biology and Medicine (Markus Braun, Peter Gilch and Wolfgang Zinth, eds.), Springer Berlin Heidelberg, pp. 201-241 (2008) Abstract
• D. Bourgeois, F. Schotte, M. Brunori, and B. Vallone.  Time-resolved methods in biophysics. 6. Time-resolved Laue crystallography as a tool to investigate photo-activated protein dynamics.  Photochem. Photobiol. Sci. 6, 1047–1056 (2007) Abstract
• K. Moffat.  Laue Crystallography: Time Resolved Studies.  In International Tables for X-Ray Crystallography, Volume F: Crystallography of Biological Macromolecules, edited by M. G. Rossmann and E. Arnold. Ch. 8.2, p. 167-176 (2006) more information
• M. Schmidt, H. Ihee, R. Pahl and V. Srajer.  Protein-ligand interactions probed by time-resolved crystallography.  In Protein-Ligand Interactions: Methods and Applications (G. U. Nienhaus, ed.), Methods in Molecular Biology, vol. 305, Humana Press, Totawa, NJ, pp. 115-154 (2005) Abstract
• D. Bourgeois and A. Royant.  Advances in kinetic protein crystallography.  Current Opinion in Structural Biology 15 (5), 538-547 (2005) Abstract
• M. Goeldner, R. Givens, eds.  Dynamic Studies in Biology: Phototriggers, Photoswitches and Caged Biomolecules.  Wiley-VCH, pp. 410–434 (2005) Abstract