Science Highlights
BioCARS: Synchrotron facility for probing structural dynamics of biological macromolecules
Henning, R. W., Kosheleva, I., Šrajer, V., Kim, I.-S., Zoellner, E., and Ranganathan, R. (2024) Structural Dynamics 11, 014301
Microsecond dynamics control the HIV-1 envelope conformation
Bennett, A. L., Edwards, R. J., Kosheleva, I., Saunders, C., Bililign, Y., Williams, A., Manosouri, K., Saunders, K. O., Haynes, B. F., Acharya, P., and Henderson, R. (2023) Microsecond dynamics control the HIV-1 envelope conformation. bioRxiv 2023.05.17.541130
Sample-minimizing co-flow cell for time-resolved pump–probe X-ray solution scattering
Kosheleva, I., Henning, R., Kim, I., Kim, S. O., Kusel, M., and Srajer, V. (2023) J Synchrotron Rad 30, 490–499
Time-resolved β-lactam cleavage by L1 metallo-β-lactamase
Wilamowski, M., Sherrell, D. A., Kim, Y., Lavens, A., Henning, R. W., Lazarski, K., Shigemoto, A., Endres, M., Maltseva, N., Babnigg, G., Burdette, S. C., Srajer, V., and Joachimiak, A. (2022) Time-resolved β-lactam cleavage by L1 metallo-β-lactamase. Nat Commun 13, 7379.
Light-Induced Protein Structural Dynamics in Bacteriophytochrome Revealed by Time-Resolved X-ray Solution Scattering
Lee, S. J., Kim, T. W., Kim, J. G., Yang, C., Yun, S. R., Kim, C., Ren, Z., Kumarapperuma, I., Kuk, J., Moffat, K., Yang, X., and Ihee, H. (2022) Light-induced protein structural dynamics in bacteriophytochrome revealed by time-resolved x-ray solution scattering. Science Advances 8, eabm6278.
On-chip Crystallization and Large-Scale Serial Diffraction at Room Temperature
Biju, L. M., Wang, C., Kang, W., Tom, I. P., Kumarapperuma, I., Yang, X., and Ren, Z. (2022) On-chip Crystallization and Large-Scale Serial Diffraction at Room Temperature. JoVE (Journal of Visualized Experiments) e63022.
Time-Resolved X-ray Scattering Studies of Proteins
Cho, H. S., Schotte, F., Stadnytskyi, V., and Anfinrud, P. (2021) Time-resolved X-ray scattering studies of proteins.
Current Opinion in Structural Biology 70, 99–107.
Effect of the Abolition of Intersubunit Salt Bridges on Allosteric Protein Structural Dynamics
Choi, M., Kim, J. G., Muniyappan, S., Kim, H., Kim, T. W., Lee, Y., Lee, S. J., Kim, S. O., and Ihee, H. (2021) Effect of the abolition of intersubunit salt bridges on allosteric protein structural dynamics.
Chem. Sci. 12, 8207–8217
Unfolding Bovine α-Lactalbumin with T-Jump: Characterizing Disordered Intermediates via Time-Resolved X-Ray Solution Scattering and Molecular Dynamics Simulations
Hsu, D. J., Leshchev, D., Kosheleva, I., Kohlstedt, K. L., and Chen, L. X. (2021)
Unfolding bovine α-lactalbumin with T-jump: Characterizing disordered intermediates via time-resolved x-ray solution scattering and molecular dynamics simulations.
J. Chem. Phys. 154, 105101.